What Are Antibodies And Its History?
An antibody is a blood protein produced by the immune system in response to the presence of a foreign substance. These foreign substances, called antigens, can include viruses, bacteria, venom, toxins, drugs, certain proteins in foods, and even red blood cells from other people.
When the body encounters a potentially dangerous antigen, it makes specific antibodies against that antigen. Antibodies recognize the appropriate antigen, bind to it, and remove it from the body. You can easily get the best antibodies products at Boster Bio featured products.
Antibodies are made in response to certain antigens and are only effective against that antigen, which means that antibodies against disease A will not be effective against antigens against disease B (so the flu vaccine will not work against coronavirus or other diseases)
Image Source: Google
History of antibody research
In 1908, doctor and scientist Paul Ehrlich received the Nobel Prize in Physiology or Medicine for his work in immunology. To understand disease resistance, Ehrlich fed laboratory mice increased doses of the toxic ricin and abrin.
A few days later, he noticed that the mice that were fed ricin developed a resistance that lasted for several months. Although they appeared to be immunized against ricin, the mice given ricin did not develop sufficient resistance to abrin and were still as susceptible to abrin as mice that were not part of the experiment.
Ehrlich then used mice to test the immunity of the offspring and ultimately concluded that the antibodies could be transmitted from mother to child in vitro or through breast milk, although the resulting immunity was not durable.
Based on his research, Ehrlich theorized that if links could be made to target pathogens selectively, toxins could be created to combat those substances.